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BMS-P5 free base

CAS No. 1550371-22-6

BMS-P5 free base ( —— )

Catalog No. M22888 CAS No. 1550371-22-6

BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.?BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 131 In Stock
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Biological Information

  • Product Name
    BMS-P5 free base
  • Note
    Research use only, not for human use.
  • Brief Description
    BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.?BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma.
  • Description
    BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.?BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma.?Administration of BMS-P5 to multiple myeloma-bearing mice delays appearance of symptoms and disease progression Targeting PAD4 may be beneficial for treatment of multiple myeloma.Administration of BMS-P5 to multiple myeloma-bearing mice delays appearance of symptoms and disease progression.?
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    peptidylarginine deiminase 4 (PAD4)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1550371-22-6
  • Formula Weight
    472.58
  • Molecular Formula
    C27H32N6O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(N1[C@@H](C)CC[C@@H](N)C1)C2=CC(OC)=C3C(N=C(C4=CC5=CC=CN=C5N4CC6CC6)N3C)=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Li M , Lin C , Deng H , et al. A novel peptidylarginine deiminase 4 (PAD4) inhibitor BMS-P5 blocks formation of neutrophil extracellular traps and delays progression of multiple myeloma[J]. Molecular Cancer Therapeutics, 2020, 19(7):molcanther.1020.2019.
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